"In this context, the PREDIMED-Plus, a new ongoing primary cardiovascular prevention trial based [on] an intensive weight-loss lifestyle intervention program, provides an unprecedented opportunity to examine the 12 month changes in weight and adiposity measures between those participants with short or adequate sleep duration and between those with low or high sleep variability," they continue.
PREDIMED-Plus is a clinical trial that studies the health effects of following a Mediterranean-style diet in a Spanish cohort. The results of the current research are part of this ongoing trial.
In the current research, Prof. Salas-Salvadó and colleagues analyzed the medical data of 1,986 individuals with a mean age of 65 years over the course of a year.
All of these participants were overweight or had obesity at baseline, and they also had metabolic syndrome, a cluster of health risk factors that include high blood pressure (hypertension), increased levels of insulin (hyperinsulinemia), low glucose tolerance, and abnormal levels of blood lipids (dyslipidemia).
For the entire year, these volunteers participated in an intensive weight loss program that included following a low calorie Mediterranean-type diet, boosting levels of physical activity, and participating in behavioral support sessions that aimed to improve habits and lifestyle.